HitPredict

Interactor 1: UBCD2 (P52485)
Ubiquitin-conjugating enzyme E2-24 kDa (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 2) (Ubiquitin carrier protein) (Ubiquitin-protein ligase)
Gene: Ubc2

Interactor 2: Q9VXP1 (Q9VXP1)
RING-type E3 ubiquitin transferase (EC 2.3.2.27)
Gene: sordd1

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	14605208
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 232 Dm			1 277
+	Dm
		854562 UBCD2_DROME (1-232): 2.16e-92: 272: 100.00		Q8IR26_DROME (1-276): 7.03e-73: 226: 91.30
+	Dm
		1337333 Q9I7T6_DROME (2-231): 4.62e-78: 240: 40.34		Q9VXP1_DROME (1-277): 7.95e-81: 246: 100.00
+	Dm
		1215059 Q9I7T6_DROME (2-231): 4.62e-78: 240: 40.34		Q8IR26_DROME (1-276): 7.03e-73: 226: 91.30
+	Hs
		1292368 UB2D4_HUMAN (87-231): 1.43e-81: 241: 64.83		RN185_HUMAN (89-277): 2.19e-53: 173: 53.16
+	Hs
		919826 UB2D2_HUMAN (87-231): 3.29e-81: 241: 65.52		RN185_HUMAN (89-277): 2.19e-53: 173: 53.16
+	Hs
		1307272 UB2D4_HUMAN (87-231): 1.43e-81: 241: 64.83		RNF5_HUMAN (103-241): 2.62e-42: 144: 55.40
+	Hs
		919838 UB2D2_HUMAN (87-231): 3.29e-81: 241: 65.52		RNF5_HUMAN (103-241): 2.62e-42: 144: 55.40
+	Hs
		919828 UB2D2_HUMAN (87-231): 3.29e-81: 241: 65.52		RN170_HUMAN (100-276): 2.88e-32: 121: 17.35
+	Hs
		919712 UB2D2_HUMAN (87-231): 3.29e-81: 241: 65.52		TRI26_HUMAN (120-235): 6.4e-30: 119: 20.80
+	Hs
		919822 UB2D2_HUMAN (87-231): 3.29e-81: 241: 65.52		TRI11_HUMAN (113-235): 5.58e-30: 118: 21.14
+	Hs
		1336390 UB2D4_HUMAN (87-231): 1.43e-81: 241: 64.83		TRI39_HUMAN (124-235): 4.92e-28: 114: 19.47
+	Hs
		584923 UB2D2_HUMAN (87-231): 3.29e-81: 241: 65.52		RO52_HUMAN (121-233): 2.97e-28: 114: 20.18
+	Hs
		919870 UB2D2_HUMAN (87-231): 3.29e-81: 241: 65.52		TRI39_HUMAN (124-235): 4.92e-28: 114: 19.47
+	Hs
		536779 UB2D2_HUMAN (87-231): 3.29e-81: 241: 65.52		TRI27_HUMAN (124-256): 1.7e-27: 112: 18.38
+	Hs
		537142 UB2D4_HUMAN (87-231): 1.43e-81: 241: 64.83		TRI27_HUMAN (124-256): 1.7e-27: 112: 18.38
+	Hs
		135019 UB2D2_HUMAN (87-231): 3.29e-81: 241: 65.52		TRI38_HUMAN (111-235): 2.98e-27: 111: 16.79
+	Hs
		135045 UB2D4_HUMAN (87-231): 1.43e-81: 241: 64.83		TRI38_HUMAN (111-235): 2.98e-27: 111: 16.79
+	Hs
		135040 UB2E2_HUMAN (37-232): 9.36e-80: 239: 72.50		TRI38_HUMAN (111-235): 2.98e-27: 111: 16.79
+	Hs
		919905 UB2D2_HUMAN (87-231): 3.29e-81: 241: 65.52		CBLC_HUMAN (56-191): 1.01e-25: 107: 22.46
+	Hs
		749339 UB2D2_HUMAN (87-231): 3.29e-81: 241: 65.52		BRCA1_HUMAN (124-174): 2.67e-16: 80.7: 35.29