HitPredict

Interactor 1: UBA2 (P52488)
Ubiquitin-activating enzyme E1-like (Polymerase-interacting protein 2) (SMT3-activating enzyme subunit 2)
Gene: UBA2

Interactor 2: SMT3 (Q12306)
Ubiquitin-like protein SMT3
Gene: SMT3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.858

Property	Details
Experiments	9312010, 20164921, 23122649
Identification Methods	affinity chromatography technology, cross-linking study, biochemical, comigration in sds page, unspecified method
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Rad60-SLD~ThiF
Common GO terms	GO:0005634 - nucleus GO:0016925 - protein sumoylation
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 636 Sc			1 101
+	Rn
		70077 B1WC32_RAT (9-636): 0: 564: 32.93		SUMO3_RAT (9-98): 1.04e-35: 119: 43.96
+	Hs
		902787 SAE2_HUMAN (9-636): 0: 552: 32.57		SUMO2_HUMAN (9-98): 2.32e-36: 120: 42.86
+	Hs
		102176 SAE2_HUMAN (9-636): 0: 552: 32.57		SUMO5_HUMAN (1-98): 4.98e-35: 117: 43.88
+	Hs
		879160 SAE2_HUMAN (9-636): 0: 552: 32.57		SUMO3_HUMAN (9-98): 2.24e-34: 115: 43.96
+	Hs
		928217 SAE2_HUMAN (9-636): 0: 552: 32.57		SUMO1_HUMAN (1-98): 2.09e-33: 112: 44.44
+	Sp
		140839 UBA2_SCHPO (13-626): 5.47e-176: 515: 36.88		PMT3_SCHPO (4-101): 2.02e-37: 123: 53.00
+	Dm
		332537 Q7KUA4_DROME (10-614): 2.31e-176: 519: 29.43		O97102_DROME (13-99): 2.66e-35: 117: 43.18
+	Hs
		607044 UBA1_HUMAN (4-153): 7.74e-32: 134: 20.00		SUMO2_HUMAN (9-98): 2.32e-36: 120: 42.86
+	Rn
		1137284 UBA1_RAT (4-394): 2.95e-31: 132: 15.58		SUMO3_RAT (9-98): 1.04e-35: 119: 43.96