HitPredict

Interactor 1: AGFG1 (P52594)
Arf-GAP domain and FG repeat-containing protein 1 (HIV-1 Rev-binding protein) (Nucleoporin-like protein RIP) (Rev-interacting protein) (Rev/Rex activation domain-binding protein)
Gene: AGFG1

Interactor 2: SMAP2 (Q8WU79)
Stromal membrane-associated protein 2 (Stromal membrane-associated protein 1-like)
Gene: SMAP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ArfGap~ArfGap
Common GO terms	GO:0005096 - GTPase activator activity GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0046872 - metal ion binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 562 Hs			1 429
+	Hs
		1222890 SMAP1_HUMAN (6-498): 1.08e-53: 191: 17.03		SMAP2_HUMAN (1-429): 3.92e-143: 416: 100.00
+	Mm
		1186512 SMAP1_MOUSE (6-498): 8.26e-52: 185: 14.11		SMAP2_MOUSE (1-429): 1.13e-140: 410: 95.34
+	Hs
		1236004 ARFG2_HUMAN (5-518): 5.75e-71: 238: 11.77		ARFG3_HUMAN (1-351): 2.62e-59: 203: 19.78
+	Mm
		1148437 GIT1_MOUSE (21-544): 4.77e-67: 233: 12.68		ASAP1_MOUSE (2-390): 1.51e-56: 203: 14.50
+	Hs
		1066128 ACAP2_HUMAN (2-249): 1.71e-60: 215: 16.35		ACAP3_HUMAN (2-165): 8.29e-56: 199: 31.55
+	Hs
		1255744 ASAP3_HUMAN (2-481): 9.03e-60: 215: 11.75		ASAP1_HUMAN (2-377): 1.83e-53: 194: 13.96
+	Zm
		29090 B4FY47_MAIZE (5-454): 5.04e-52: 185: 19.60		A0A1D6JYA9_MAIZE (13-362): 3.7e-58: 199: 18.82
+	Hs
		1357702 AGAP1_HUMAN (2-129): 3.57e-26: 115: 23.26		AGAP1_HUMAN (3-126): 2.32e-42: 161: 37.80
+	Hs
		1299064 AGAP1_HUMAN (2-129): 3.57e-26: 115: 23.26		AGAP3_HUMAN (16-137): 5.18e-42: 160: 36.80
+	Ce
		1376915 CNT1_CAEEL (16-187): 5.43e-26: 114: 20.64		CNT1_CAEEL (25-123): 2.96e-17: 86.3: 38.68