HitPredict

Interactor 1: HNRPF (P52597)
Heterogeneous nuclear ribonucleoprotein F (hnRNP F) (Nucleolin-like protein mcs94-1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein F, N-terminally processed]
Gene: HNRNPF

Interactor 2: RBM7 (Q9Y580)
RNA-binding protein 7 (RNA-binding motif protein 7)
Gene: RBM7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1, RRM_1~zf-RNPHF
Common GO terms	GO:0003723 - RNA binding GO:0003727 - single-stranded RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 415 Hs			1 266
+	Hs
		683039 HNRH1_HUMAN (1-413): 9.99e-69: 226: 74.82		RBM7_HUMAN (1-266): 2.96e-58: 188: 100.00
+	Hs
		516495 PABP1_HUMAN (1-410): 4.49e-80: 260: 13.66		PABP4_HUMAN (4-262): 1.83e-39: 146: 15.14
+	Hs
		516339 PABP1_HUMAN (1-410): 4.49e-80: 260: 13.66		PABP1_HUMAN (4-256): 1.02e-38: 144: 14.71
+	Hs
		516689 PABP1_HUMAN (1-410): 4.49e-80: 260: 13.66		PABP3_HUMAN (11-256): 9.43e-37: 139: 13.81
+	Hs
		516471 PABP1_HUMAN (1-410): 4.49e-80: 260: 13.66		TIAR_HUMAN (2-205): 1.07e-30: 119: 16.30
+	Hs
		516484 PABP1_HUMAN (1-410): 4.49e-80: 260: 13.66		ELAV2_HUMAN (2-205): 9.2e-23: 97.4: 16.09
+	Mm
		665745 PABP1_MOUSE (1-410): 5.26e-80: 260: 13.66		TIA1_MOUSE (3-187): 3.59e-16: 79: 14.21
+	Mm
		857399 HNRPF_MOUSE (1-415): 2.75e-77: 247: 98.07		TIA1_MOUSE (3-187): 3.59e-16: 79: 14.21
+	Hs
		855070 HNRPF_HUMAN (1-415): 1.26e-75: 242: 100.00		SF3B4_HUMAN (7-242): 3.59e-15: 76.6: 15.39
+	Mm
		193432 HNRH1_MOUSE (1-413): 9.27e-69: 226: 74.82		TIA1_MOUSE (3-187): 3.59e-16: 79: 14.21
+	Hs
		682823 HNRH1_HUMAN (1-413): 9.99e-69: 226: 74.82		SF3B4_HUMAN (7-242): 3.59e-15: 76.6: 15.39
+	Sc
		376562 PABP_YEAST (11-296): 1.71e-42: 158: 11.60		PABP_YEAST (10-258): 4.72e-37: 139: 15.22
+	Hs
		474021 PABP4_HUMAN (3-299): 6.9e-46: 169: 12.17		PAB4L_HUMAN (4-171): 1.42e-33: 126: 14.52
+	Hs
		1020249 PABP4_HUMAN (3-299): 6.9e-46: 169: 12.17		ELAV2_HUMAN (2-205): 9.2e-23: 97.4: 16.09
+	Hs
		474019 PAB4L_HUMAN (3-188): 1.33e-38: 144: 14.51		ELAV2_HUMAN (2-205): 9.2e-23: 97.4: 16.09
+	Sc
		376694 PABP_YEAST (11-296): 1.71e-42: 158: 11.60		PUB1_YEAST (6-108): 4.83e-15: 76.3: 30.10
+	Sc
		376645 PABP_YEAST (11-296): 1.71e-42: 158: 11.60		RNA15_YEAST (10-88): 8.43e-15: 74.4: 33.75