Interactor 1: CRK (P46108)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK

Interactor 2: DOK7 (Q18PE1)
Protein Dok-7 (Downstream of tyrosine kinase 7)
Gene: DOK7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.58 0.55 0.569

The method score is based on:

Property Details
Experiments 25814554, unassigned1126
Identification Methods two hybrid, two hybrid array, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0007167 - enzyme-linked receptor protein signaling pathway
GO:0031594 - neuromuscular junction
GO:0035022 - positive regulation of Rac protein signal transduction
GO:0035591 - signaling adaptor activity
GO:1904395 - positive regulation of skeletal muscle acetylcholine-gated channel clustering
Homologous interactions 0

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Last updated: 11Aug2025