Interactor 1: FGD1 (P52734)
FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF) (Zinc finger FYVE domain-containing protein 3)
Gene: FGD1
Interactor 2: SRC8 (Q60598)
Src substrate cortactin
Gene: Cttn
Species: Mus musculus
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.57 | 1.00 | 0.756 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12913069 |
| Identification Methods | two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, filter binding |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PH~SH3_9, RhoGEF~SH3_9 |
| Common GO terms | GO:0001726 - ruffle GO:0005737 - cytoplasm GO:0005794 - Golgi apparatus GO:0030027 - lamellipodium GO:0030036 - actin cytoskeleton organization |
| Homologous interactions | 19 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
