HitPredict

Interactor 1: CRK (P46108)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK

Interactor 2: PCDA8 (Q9Y5H6)
Protocadherin alpha-8 (PCDH-alpha-8)
Gene: PCDHA8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 304 Hs			1 950
+	Hs
		855829 CRK_HUMAN (1-304): 1.27e-69: 220: 100.00		PCDA1_HUMAN (1-950): 0: 1109: 81.05
+	Hs
		855826 CRK_HUMAN (1-304): 1.27e-69: 220: 100.00		PCDA2_HUMAN (1-950): 0: 1106: 79.58
+	Hs
		855806 CRK_HUMAN (1-304): 1.27e-69: 220: 100.00		PCDA6_HUMAN (1-950): 0: 1105: 90.53
+	Hs
		855825 CRK_HUMAN (1-304): 1.27e-69: 220: 100.00		PCDA3_HUMAN (1-950): 0: 1105: 82.21
+	Hs
		855827 CRK_HUMAN (1-304): 1.27e-69: 220: 100.00		PCDAB_HUMAN (1-950): 0: 1105: 81.47
+	Hs
		855824 CRK_HUMAN (1-304): 1.27e-69: 220: 100.00		PCDA5_HUMAN (24-950): 0: 1093: 82.74
+	Hs
		855828 CRK_HUMAN (1-304): 1.27e-69: 220: 100.00		PCDAA_HUMAN (4-950): 0: 1081: 81.73
+	Hs
		855822 CRK_HUMAN (1-304): 1.27e-69: 220: 100.00		PCDA9_HUMAN (24-950): 0: 1079: 81.12
+	Hs
		855807 CRK_HUMAN (1-304): 1.27e-69: 220: 100.00		PCDAC_HUMAN (1-950): 0: 1066: 80.74
+	Hs
		855805 CRK_HUMAN (1-304): 1.27e-69: 220: 100.00		PCDA7_HUMAN (3-374): 2.9e-61: 227: 23.36
+	Hs
		988067 GRB2_HUMAN (135-297): 1.31e-26: 106: 17.05		PCDB5_HUMAN (358-877): 4.07e-66: 239: 17.09