HitPredict

Interactor 1: EFNB2 (P52799)
Ephrin-B2 (EPH-related receptor tyrosine kinase ligand 5) (LERK-5) (HTK ligand) (HTK-L)
Gene: EFNB2

Interactor 2: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0098978 - glutamatergic synapse
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 333 Hs			1 193
+	Hs
		856523 EFNB2_HUMAN (1-333): 0: 517: 100.00		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		856515 EFNB2_HUMAN (1-333): 0: 517: 100.00		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		856514 EFNB2_HUMAN (1-333): 0: 517: 100.00		RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54
+	Hs
		856522 EFNB2_HUMAN (1-333): 0: 517: 100.00		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94
+	Hs
		900377 EFNB1_HUMAN (9-333): 2.72e-167: 471: 54.23		RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00
+	Hs
		925193 EFNB1_HUMAN (9-333): 2.72e-167: 471: 54.23		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		436254 EFNB1_HUMAN (9-333): 2.72e-167: 471: 54.23		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Hs
		950924 EFNB1_HUMAN (9-333): 2.72e-167: 471: 54.23		RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40
+	Hs
		893900 EFNB1_HUMAN (9-333): 2.72e-167: 471: 54.23		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		545322 EFNB1_HUMAN (9-333): 2.72e-167: 471: 54.23		RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61
+	Hs
		892317 EFNB1_HUMAN (9-333): 2.72e-167: 471: 54.23		RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54
+	Hs
		915606 EFNB1_HUMAN (9-333): 2.72e-167: 471: 54.23		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94
+	Hs
		120388 EFNB1_HUMAN (9-333): 2.72e-167: 471: 54.23		RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98
+	Hs
		856359 EFNA4_HUMAN (12-198): 5.39e-58: 187: 24.34		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22