Interactor 1: NDST1 (P52848)
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 (Glucosaminyl N-deacetylase/N-sulfotransferase 1) (NDST-1) (N-heparan sulfate sulfotransferase 1) (N-HSST 1) ([Heparan sulfate]-glucosamine N-sulfotransferase 1) (HSNST 1) [Includes: Heparan sulfate N-deacetylase 1 (EC 3.5.1.-); Heparan sulfate N-sulfotransferase 1 (EC 2.8.2.8)]
Gene: NDST1

Interactor 2: NDST2 (P52849)
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST-2) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 2 (EC 2.8.2.-)]
Gene: NDST2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Sulfotransfer_1~Sulfotransfer_1
Common GO terms GO:0000139 - Golgi membrane
GO:0005794 - Golgi apparatus
GO:0015014 - heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
GO:0015015 - heparan sulfate proteoglycan biosynthetic process, enzymatic modification
GO:0015016 - [heparan sulfate]-glucosamine N-sulfotransferase activity
and 4 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 882
Hs

1 883
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024