HitPredict

Interactor 1: CAZA1 (P52907)
F-actin-capping protein subunit alpha-1 (CapZ alpha-1)
Gene: CAPZA1

Interactor 2: SH3K1 (Q96B97)
SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1)
Gene: SH3KBP1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.714

Property	Details
Experiments	28514442, 31980649, 33961781, unassigned2173, 23178720
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005856 - cytoskeleton
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 286 Hs			1 665
+	Hs
		813121 CAZA2_HUMAN (1-286): 6.84e-159: 445: 86.71		SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00
+	Hs
		857263 CAZA1_HUMAN (1-286): 1.77e-164: 459: 100.00		CD2AP_HUMAN (1-664): 1.16e-98: 317: 32.22
+	Hs
		813227 CAZA2_HUMAN (1-286): 6.84e-159: 445: 86.71		CD2AP_HUMAN (1-664): 1.16e-98: 317: 32.22
+	Hs
		857099 CAZA1_HUMAN (1-286): 1.77e-164: 459: 100.00		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Hs
		298962 CAZA2_HUMAN (1-286): 6.84e-159: 445: 86.71		SRBS2_HUMAN (3-155): 4.65e-11: 68.2: 30.86