HitPredict

Interactor 1: TIA1 (P52912)
Cytotoxic granule associated RNA binding protein TIA1 (Nucleolysin TIA-1) (RNA-binding protein TIA-1) (T-cell-restricted intracellular antigen-1) (TIA-1)
Gene: TIA1

Interactor 2: RU17 (Q62376)
U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70)
Gene: Snrnp70

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	27160897
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1, RRM_1~U1snRNP70_N
Common GO terms	GO:0005634 - nucleus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 386 Mm			1 448
+	Mm
		665745 TIA1_MOUSE (1-386): 2.66e-116: 345: 100.00		PABP1_MOUSE (4-378): 1.73e-51: 185: 10.62
+	Hs
		441896 TIA1_HUMAN (1-386): 2.53e-114: 340: 96.63		RU17_HUMAN (1-448): 6.21e-46: 166: 92.00
+	Hs
		680439 TIA1_HUMAN (1-386): 2.53e-114: 340: 96.63		TIAR_HUMAN (3-236): 4.9e-28: 116: 12.61
+	Hs
		680422 TIA1_HUMAN (1-386): 2.53e-114: 340: 96.63		TIA1_HUMAN (3-232): 5.92e-26: 110: 13.04
+	Hs
		516339 PABP1_HUMAN (3-303): 6.45e-67: 224: 24.68		PABP1_HUMAN (4-378): 2.97e-52: 187: 10.62
+	Hs
		441852 PABP1_HUMAN (3-303): 6.45e-67: 224: 24.68		RU17_HUMAN (1-448): 6.21e-46: 166: 92.00
+	Hs
		516635 PABP1_HUMAN (3-303): 6.45e-67: 224: 24.68		PABP5_HUMAN (4-361): 1.47e-33: 131: 9.28
+	Hs
		516495 PABP1_HUMAN (3-303): 6.45e-67: 224: 24.68		PABP4_HUMAN (3-267): 8.7e-30: 124: 11.31
+	Hs
		516689 PABP1_HUMAN (3-303): 6.45e-67: 224: 24.68		PABP3_HUMAN (7-316): 1.86e-29: 123: 11.18
+	Hs
		516471 PABP1_HUMAN (3-303): 6.45e-67: 224: 24.68		TIAR_HUMAN (3-236): 4.9e-28: 116: 12.61
+	Hs
		442076 TIAR_HUMAN (98-295): 6.66e-36: 136: 24.02		RU17_HUMAN (1-448): 6.21e-46: 166: 92.00
+	Sc
		694189 PUB1_YEAST (7-185): 3.03e-31: 125: 40.56		RU17_YEAST (3-282): 7.06e-46: 162: 27.97
+	Hs
		474034 PAB4L_HUMAN (103-303): 2.43e-39: 145: 22.93		PABP5_HUMAN (4-361): 1.47e-33: 131: 9.28
+	Hs
		474021 PAB4L_HUMAN (103-303): 2.43e-39: 145: 22.93		PABP4_HUMAN (3-267): 8.7e-30: 124: 11.31
+	Hs
		963504 TIAR_HUMAN (98-295): 6.66e-36: 136: 24.02		TIAR_HUMAN (3-236): 4.9e-28: 116: 12.61
+	Sc
		376694 PUB1_YEAST (7-185): 3.03e-31: 125: 40.56		PABP_YEAST (2-264): 2.1e-27: 116: 13.11