HitPredict

Interactor 1: NUP98 (P52948)
Nuclear pore complex protein Nup98-Nup96 (EC 3.4.21.-) [Cleaved into: Nuclear pore complex protein Nup98 (98 kDa nucleoporin) (Nucleoporin Nup98) (Nup98); Nuclear pore complex protein Nup96 (96 kDa nucleoporin) (Nucleoporin Nup96) (Nup96)]
Gene: NUP98

Interactor 2: NUP98 (P52948)
Nuclear pore complex protein Nup98-Nup96 (EC 3.4.21.-) [Cleaved into: Nuclear pore complex protein Nup98 (98 kDa nucleoporin) (Nucleoporin Nup98) (Nup98); Nuclear pore complex protein Nup96 (96 kDa nucleoporin) (Nucleoporin Nup96) (Nup96)]
Gene: NUP98

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 35679425, 29439243
Identification Methods pull down, x-ray crystallography
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Nucleoporin2~Nucleoporin2, Nup96~Nup96
Common GO terms GO:0000973 - post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
GO:0003713 - transcription coactivator activity
GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0005635 - nuclear envelope
and 25 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 1817
Hs

1 1817
+ Hs
+ Hs
+ Ce
+ Sc
+ Sc
+ Dm
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Dm
+ Mm
+ Dm
+ Dm
+ Rn
+ Sc
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024