Interactor 1: NUP98 (P52948)
Nuclear pore complex protein Nup98-Nup96 (EC 3.4.21.-) [Cleaved into: Nuclear pore complex protein Nup98 (98 kDa nucleoporin) (Nucleoporin Nup98) (Nup98); Nuclear pore complex protein Nup96 (96 kDa nucleoporin) (Nucleoporin Nup96) (Nup96)]
Gene: NUP98

Interactor 2: NU107 (P57740)
Nuclear pore complex protein Nup107 (107 kDa nucleoporin) (Nucleoporin Nup107)
Gene: NUP107

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.958

The method score is based on:

Property Details
Experiments 35271311, 24927568, 26496610, 24981860, 20676042, 17360435, 11564755
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Nup84_Nup100~Nup96
Common GO terms GO:0000973 - post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
GO:0005635 - nuclear envelope
GO:0005643 - nuclear pore
GO:0005829 - cytosol
GO:0006606 - protein import into nucleus
and 6 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 1817
Hs

1 925
+ Hs
+ Hs
+ Cg
+ Tt
+ Sc
+ Sc
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024