HitPredict

Interactor 1: NKX25 (P52952)
Homeobox protein Nkx-2.5 (Cardiac-specific homeobox) (Homeobox protein CSX) (Homeobox protein NK-2 homolog E)
Gene: NKX2-5

Interactor 2: SRRM2 (Q9UQ35)
Serine/arginine repetitive matrix protein 2 (300 kDa nuclear matrix antigen) (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (SR-related nuclear matrix protein of 300 kDa) (Ser/Arg-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (Tax-responsive enhancer element-binding protein 803) (TaxREB803)
Gene: SRRM2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35140242
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 324 Hs			1 2752
+	Hs
		858119 NKX25_HUMAN (1-324): 9.3e-62: 201: 100.00		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		1300937 NKX24_HUMAN (1-240): 1.37e-41: 149: 32.45		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		620192 PAX7_HUMAN (113-321): 3.33e-33: 129: 20.18		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		641431 PAX6_HUMAN (83-321): 6.21e-31: 122: 17.89		PRC2B_HUMAN (640-2750): 5.74e-64: 245: 9.36
+	Hs
		620250 PAX3_HUMAN (112-321): 5.64e-31: 123: 20.61		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		641534 PAX6_HUMAN (83-321): 6.21e-31: 122: 17.89		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		1263870 NANOG_HUMAN (58-291): 5.12e-37: 136: 22.65		MUC16_HUMAN (111-2747): 6.13e-36: 153: 10.09
+	Mm
		976069 MSX2_MOUSE (67-253): 1.44e-36: 133: 26.70		MINT_MOUSE (20-1829): 2.72e-32: 141: 8.77
+	Mm
		1194722 NANOG_MOUSE (27-293): 2.18e-36: 134: 25.00		NCOR2_MOUSE (1288-2719): 2e-19: 99: 10.73
+	Hs
		641445 PAX6_HUMAN (83-321): 6.21e-31: 122: 17.89		NIPBL_HUMAN (333-1474): 1.68e-16: 89.1: 14.39
+	Hs
		679119 TLX1_HUMAN (66-243): 2.32e-31: 121: 23.60		NIPBL_HUMAN (333-1474): 1.68e-16: 89.1: 14.39
+	Mm
		1194626 NANOG_MOUSE (27-293): 2.18e-36: 134: 25.00		DIDO1_MOUSE (277-1360): 4.81e-12: 74.3: 7.72
+	Mm
		101829 NANOG_MOUSE (27-293): 2.18e-36: 134: 25.00		F8WI37_MOUSE (2097-2749): 1.31e-09: 66.6: 8.68
+	Mm
		1194614 NANOG_MOUSE (27-293): 2.18e-36: 134: 25.00		KMT2C_MOUSE (2097-2749): 1.31e-09: 66.6: 8.68
+	Hs
		620175 PAX7_HUMAN (113-321): 3.33e-33: 129: 20.18		KMT2C_HUMAN (1760-2747): 2.06e-09: 65.9: 9.01
+	Hs
		152588 PAX7_HUMAN (113-321): 3.33e-33: 129: 20.18		KMT2D_HUMAN (10-501): 7.91e-09: 63.9: 11.75
+	Hs
		641482 PAX6_HUMAN (83-321): 6.21e-31: 122: 17.89		KMT2C_HUMAN (1760-2747): 2.06e-09: 65.9: 9.01
+	Hs
		679137 TLX1_HUMAN (66-243): 2.32e-31: 121: 23.60		KMT2C_HUMAN (1760-2747): 2.06e-09: 65.9: 9.01
+	Hs
		152592 PAX6_HUMAN (83-321): 6.21e-31: 122: 17.89		KMT2D_HUMAN (10-501): 7.91e-09: 63.9: 11.75
+	Hs
		152596 TLX1_HUMAN (66-243): 2.32e-31: 121: 23.60		KMT2D_HUMAN (10-501): 7.91e-09: 63.9: 11.75