HitPredict

Interactor 1: TXTP (P53007)
Tricarboxylate transport protein, mitochondrial (Citrate transport protein) (CTP) (Mitochondrial citrate carrier) (CIC) (Solute carrier family 25 member 1) (Tricarboxylate carrier protein)
Gene: SLC25A1

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	24725412
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005743 - mitochondrial inner membrane GO:0070062 - extracellular exosome
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 311 Hs			1 2527
+	Hs
		90255 D9HTE9_HUMAN (3-311): 1.69e-98: 294: 92.26		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		73279 B4E290_HUMAN (112-311): 1e-48: 170: 22.50		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1130213 Q6NVC0_HUMAN (112-310): 6.59e-36: 133: 23.22		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		397411 ADT2_HUMAN (116-310): 3.42e-36: 133: 23.67		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1123866 Q59EI9_HUMAN (121-310): 5.07e-35: 131: 22.28		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		3090 A0A0S2Z3H3_HUMAN (115-309): 1.18e-35: 131: 22.22		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		518152 ADT1_HUMAN (115-309): 1.18e-35: 131: 22.22		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		518382 ADT3_HUMAN (121-310): 2.98e-35: 131: 22.28		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1121048 Q53GR7_HUMAN (1-117): 6.13e-25: 106: 26.89		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1130602 GHC1_HUMAN (21-297): 1.35e-25: 105: 27.42		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		397303 ADT2_HUMAN (116-310): 3.42e-36: 133: 23.67		CSK_HUMAN (1722-2140): 2.25e-102: 339: 20.74