HitPredict

Interactor 1: ERG25 (P53045)
C-4 methylsterol oxidase ERG25 (EC 1.14.18.-) (Ergosterol biosynthetic protein 25) (Sterol-C4-methyl oxidase ERG25) (SMO)
Gene: ERG25

Interactor 2: ERG26 (P53199)
Sterol-4-alpha-carboxylate 3-dehydrogenase ERG26, decarboxylating (EC 1.1.1.170) (C-3 sterol dehydrogenase ERG26) (C-4 decarboxylase ERG26) (Ergosterol biosynthetic protein 26)
Gene: ERG26

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.660

Property	Details
Experiments	11279045, 16300994, 12119386
Identification Methods	two hybrid, protein complementation assay, anti tag coimmunoprecipitation, ubiquitin reconstruction
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0006696 - ergosterol biosynthetic process
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 309 Sc			1 349
+	Sc
		688611 ERG3_YEAST (52-307): 6.45e-44: 155: 17.90		ERG26_YEAST (1-349): 4.97e-105: 313: 100.00
+	Hs
		276539 SC5D_HUMAN (137-309): 6.73e-43: 151: 23.12		3BHS7_HUMAN (8-346): 1.17e-72: 231: 26.12