Interactor 1: MCM6 (P53091)
DNA replication licensing factor MCM6 (EC 3.6.4.12) (Minichromosome maintenance protein 6)
Gene: MCM6

Interactor 2: ORC4 (P54791)
Origin recognition complex subunit 4 (Origin recognition complex 56 kDa subunit)
Gene: ORC4

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 33741931
Identification Methods x-ray crystallography
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains MCM~ORC4_C, MCM6_C~ORC4_C, MCM_lid~ORC4_C
Common GO terms GO:0003688 - DNA replication origin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005656 - nuclear pre-replicative complex
GO:0006267 - pre-replicative complex assembly involved in nuclear cell cycle DNA replication
and 2 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1017
Sc

1 529
+ Sc
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024