Interactor 1: MCM6 (P53091)
DNA replication licensing factor MCM6 (EC 3.6.4.12) (Minichromosome maintenance protein 6)
Gene: MCM6

Interactor 2: SLD5 (Q03406)
DNA replication complex GINS protein SLD5
Gene: SLD5

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.975

The method score is based on:

Property Details
Experiments 37968396, 21362622, 21868389, 25342810, 23499444, 26255844, 16531994, 25313033, 30104407, 32804080, 32075754, 34700328, 22325992
Identification Methods affinity chromatography technology, pull down, biochemical
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains MCM~Sld5, MCM_N~Sld5
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0005634 - nucleus
GO:0006268 - DNA unwinding involved in DNA replication
GO:0031261 - DNA replication preinitiation complex
GO:0031298 - replication fork protection complex
and 2 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 1017
Sc

1 294
+ Sc
+ Mm
+ Hs
+ Sc
+ Sc
+ Hs
+ Mm
+ Dm
+ Mm
+ Hs
+ Mm
+ Hs
+ Dm
+ Hs
+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024