Interactor 1: MCM6 (P53091)
DNA replication licensing factor MCM6 (EC 3.6.4.12) (Minichromosome maintenance protein 6)
Gene: MCM6
Interactor 2: CDC45 (Q08032)
Cell division control protein 45
Gene: CDC45
Species: Saccharomyces cerevisiae S288C
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.981 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26854664, 25870112, 37968396, 15755447, 26255844, 17018296, 28869037, 25313033, 25659432, 28510759, 28373564, 31765407, 32804080, 21362622, 21179020 |
| Identification Methods | anti tag coimmunoprecipitation, affinity chromatography technology, pull down, biochemical, tandem affinity purification |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CDC45~MCM_lid, CDC45~MCM_N, CDC45~MCM_OB |
| Common GO terms | GO:0000727 - double-strand break repair via break-induced replication GO:0003688 - DNA replication origin binding GO:0003697 - single-stranded DNA binding GO:0005634 - nucleus GO:0006268 - DNA unwinding involved in DNA replication and 5 others more... |
| Homologous interactions | 18 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
