HitPredict

Interactor 1: PRP43 (P53131)
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43 (EC 3.6.4.13) (Helicase JA1)
Gene: PRP43

Interactor 2: UTP15 (Q04305)
U3 small nucleolar RNA-associated protein 15 (U3 snoRNA-associated protein 15) (U three protein 15) (U3 protein 15 required for transcription) (t-UTP15)
Gene: UTP15

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	16227579
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0005730 - nucleolus GO:0006364 - rRNA processing GO:0030490 - maturation of SSU-rRNA GO:0030686 - 90S preribosome and 1 others more... GO:0032040 - small-subunit processome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 767 Sc			1 513
+	Hs
		224824 DHX16_HUMAN (2-750): 0: 702: 42.88		FBXW7_HUMAN (5-371): 7.23e-77: 257: 14.47
+	Zm
		18259 A0A1D6H4I5_MAIZE (7-762): 0: 769: 45.31		A0A1D6J4G2_MAIZE (288-428): 9.29e-21: 97.6: 13.29
+	Sc
		630874 PRP43_YEAST (1-753): 0: 803: 100.00		NLE1_YEAST (2-66): 1.92e-09: 61.8: 10.29
+	Hs
		1055447 DHX8_HUMAN (7-765): 0: 748: 45.07		SNR40_HUMAN (2-105): 9.6e-19: 89.5: 10.44
+	Hs
		195393 DHX15_HUMAN (72-743): 0: 753: 65.48		WDR5_HUMAN (333-420): 2.73e-12: 69.9: 10.23
+	Hs
		1268324 PRP16_HUMAN (4-767): 0: 718: 38.69		SNR40_HUMAN (2-105): 9.6e-19: 89.5: 10.44
+	Hs
		224827 DHX16_HUMAN (2-750): 0: 702: 42.88		SNR40_HUMAN (2-105): 9.6e-19: 89.5: 10.44
+	Hs
		1288306 DHX35_HUMAN (46-738): 0: 651: 43.28		SNR40_HUMAN (2-105): 9.6e-19: 89.5: 10.44