Interactor 1: DUO1 (P53168)
DASH complex subunit DUO1 (Death upon overproduction protein 1) (Outer kinetochore protein DUO1)
Gene: DUO1

Interactor 2: DAM1 (P53267)
DASH complex subunit DAM1 (DUO1 and MPS1-interacting protein 1) (Kinetochore assembly protein DAM1) (Outer kinetochore protein DAM1)
Gene: DAM1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.90 0.933

The method score is based on:

Property Details
Experiments 11553702, 10688190, 11756468, 11283351, 9817759, 25751138, 11149931, 12925767, 17634282, 37968396, 32997987, 20730753, 34313341, 23267104
Identification Methods coimmunoprecipitation, two hybrid, cosedimentation through density gradient, two hybrid pooling approach, molecular sieving, affinity chromatography technology, pull down, miniaturized immunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains DASH_Dam1~DASH_Duo1
Common GO terms GO:0005737 - cytoplasm
GO:0008608 - attachment of spindle microtubules to kinetochore
GO:0031116 - positive regulation of microtubule polymerization
GO:0042729 - DASH complex
GO:0051301 - cell division
and 4 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024