HitPredict

Interactor 1: DUO1 (P53168)
DASH complex subunit DUO1 (Death upon overproduction protein 1) (Outer kinetochore protein DUO1)
Gene: DUO1

Interactor 2: DAD4 (P69851)
DASH complex subunit DAD4 (DUO1 and DAM1-interacting protein 4) (Helper of ASK1 protein 2) (Outer kinetochore protein DAD4)
Gene: DAD4

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.90	0.838

The method score is based on:

Property	Details
Experiments	16554755, 17634282, 34313341, 37968396
Identification Methods	affinity chromatography technology, two hybrid, tandem affinity purification
Interaction Type	physical association, direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	DASH_Dad4~DASH_Duo1
Common GO terms	GO:0005737 - cytoplasm GO:0005874 - microtubule GO:0008608 - attachment of spindle microtubules to kinetochore GO:0031116 - positive regulation of microtubule polymerization GO:0042729 - DASH complex and 5 others more... GO:0051301 - cell division GO:0051987 - positive regulation of attachment of spindle microtubules to kinetochore GO:0072686 - mitotic spindle GO:1990758 - mitotic sister chromatid biorientation GO:1990976 - protein transport along microtubule to mitotic spindle pole body
Homologous interactions	0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024