HitPredict

Interactor 1: NMA2 (P53204)
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 (NMN/NaMN adenylyltransferase 2) (EC 2.7.7.1) (EC 2.7.7.18) (NAD(+) diphosphorylase 2) (NAD(+) pyrophosphorylase 2) (Nicotinamide-nucleotide adenylyltransferase 2) (NMN adenylyltransferase 2) (NMNAT 2) (Nicotinate-nucleotide adenylyltransferase 2) (NaMN adenylyltransferase 2) (NaMNAT 2)
Gene: NMA2

Interactor 2: NMA1 (Q06178)
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 (NMN/NaMN adenylyltransferase 1) (EC 2.7.7.1) (EC 2.7.7.18) (NAD(+) diphosphorylase 1) (NAD(+) pyrophosphorylase 1) (Nicotinamide-nucleotide adenylyltransferase 1) (NMN adenylyltransferase 1) (NMNAT 1) (Nicotinate-nucleotide adenylyltransferase 1) (NaMN adenylyltransferase 1) (NaMNAT 1)
Gene: NMA1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.966

The method score is based on:

Property Details
Experiments 11283351, 10688190, 16554755, 37968396, 18719252, 20826334, 16429126, unassigned1933
Identification Methods two hybrid pooling approach, two hybrid, affinity chromatography technology, tandem affinity purification, dihydrofolate reductase reconstruction
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CTP_transf_like~CTP_transf_like
Common GO terms GO:0000309 - nicotinamide-nucleotide adenylyltransferase activity
GO:0004515 - nicotinate-nucleotide adenylyltransferase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0009435 - NAD biosynthetic process
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 395
Sc

1 401
+ Sc
+ Sc
+ Sp
+ Hs
+ Ce

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Last updated: 15 Jul 2024