HitPredict

Interactor 1: RSC1 (P53236)
Chromatin structure-remodeling complex subunit RSC1 (RSC complex subunit RSC1) (Remodel the structure of chromatin complex subunit 1)
Gene: RSC1

Interactor 2: RSC4 (Q02206)
Chromatin structure-remodeling complex subunit RSC4 (RSC complex subunit RSC4) (Remodel the structure of chromatin complex subunit 4)
Gene: RSC4

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.91	1.00	0.954

Property	Details
Experiments	16429126, 37968396, 11336698, 16554755, 32496195, 22359657, 21179020
Identification Methods	affinity chromatography technology, biochemical, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Bromodomain~Bromodomain
Common GO terms	GO:0000785 - chromatin GO:0003682 - chromatin binding GO:0006337 - nucleosome disassembly GO:0006338 - chromatin remodeling GO:0006368 - transcription elongation by RNA polymerase II and 1 others more... GO:0016586 - RSC-type complex
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 928 Sc			1 625
+	Sc
		969425 RSC2_YEAST (8-816): 0: 578: 46.49		RSC4_YEAST (1-625): 0: 597: 100.00
+	Sc
		860448 RSC1_YEAST (1-928): 0: 888: 100.00		RSC2_YEAST (55-196): 1.71e-13: 76.1: 19.01
+	Sc
		728765 RSC2_YEAST (8-816): 0: 578: 46.49		BDF1_YEAST (117-384): 5.12e-22: 102: 15.22
+	Sc
		975973 RSC2_YEAST (8-816): 0: 578: 46.49		GCN5_YEAST (5-160): 4.11e-20: 95.3: 16.77
+	Sc
		987568 RSC2_YEAST (8-816): 0: 578: 46.49		RSC2_YEAST (55-196): 1.71e-13: 76.1: 19.01
+	Hs
		1067068 BRD3_HUMAN (4-345): 9.76e-74: 259: 17.51		PHIP_HUMAN (16-470): 3.23e-64: 232: 15.67
+	Hs
		1067030 BRD3_HUMAN (4-345): 9.76e-74: 259: 17.51		PB1_HUMAN (24-312): 2.23e-43: 169: 18.37
+	Hs
		600145 BRD3_HUMAN (4-345): 9.76e-74: 259: 17.51		TAF1_HUMAN (128-301): 1.03e-20: 99.6: 12.57
+	Hs
		1164179 PHIP_HUMAN (3-246): 4.84e-34: 143: 21.05		BRWD3_HUMAN (32-468): 6.52e-58: 213: 16.33
+	Hs
		846993 BRDT_HUMAN (1-496): 1.03e-76: 271: 15.46		SMCA4_HUMAN (56-148): 3.01e-12: 72.1: 33.00
+	Hs
		244534 BRDT_HUMAN (1-496): 1.03e-76: 271: 15.46		BRD4_HUMAN (79-180): 1.04e-11: 70.2: 19.05
+	Hs
		1067017 BRD3_HUMAN (4-345): 9.76e-74: 259: 17.51		ATAD2_HUMAN (16-374): 2.41e-14: 78.8: 12.14
+	Hs
		846977 BRD3_HUMAN (4-345): 9.76e-74: 259: 17.51		SMCA4_HUMAN (56-148): 3.01e-12: 72.1: 33.00
+	Hs
		846778 BRD3_HUMAN (4-345): 9.76e-74: 259: 17.51		SMCA2_HUMAN (78-148): 9.33e-12: 70.5: 34.72
+	Hs
		244464 BRD3_HUMAN (4-345): 9.76e-74: 259: 17.51		BRD4_HUMAN (79-180): 1.04e-11: 70.2: 19.05
+	Hs
		1199169 PHIP_HUMAN (3-246): 4.84e-34: 143: 21.05		PB1_HUMAN (24-312): 2.23e-43: 169: 18.37
+	Hs
		600197 PHIP_HUMAN (3-246): 4.84e-34: 143: 21.05		TAF1_HUMAN (128-301): 1.03e-20: 99.6: 12.57
+	Hs
		847033 PHIP_HUMAN (3-246): 4.84e-34: 143: 21.05		SMCA4_HUMAN (56-148): 3.01e-12: 72.1: 33.00
+	Hs
		244704 PHIP_HUMAN (3-246): 4.84e-34: 143: 21.05		BRD4_HUMAN (79-180): 1.04e-11: 70.2: 19.05