HitPredict

Interactor 1: SYF2 (P53277)
Pre-mRNA-splicing factor SYF2 (PRP19 complex protein 31) (Synthetic lethal with CDC40 protein 2)
Gene: SYF2

Interactor 2: SYF1 (Q04048)
Pre-mRNA-splicing factor SYF1 (PRP19-associated complex protein 90) (Synthetic lethal with CDC40 protein 1)
Gene: SYF1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.752

The method score is based on:

Property	Details
Experiments	11283351, 11842115, 11102353, 10688190, 18719252, 16554755, 19617314, 37968396
Identification Methods	two hybrid pooling approach, two hybrid, affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0000974 - Prp19 complex GO:0005634 - nucleus GO:0005829 - cytosol GO:0071004 - U2-type prespliceosome and 3 others more... GO:0071006 - U2-type catalytic step 1 spliceosome GO:0071007 - U2-type catalytic step 2 spliceosome GO:0071008 - U2-type post-mRNA release spliceosomal complex
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	215
Sc

1	859

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024