HitPredict

Interactor 1: SYF2 (P53277)
Pre-mRNA-splicing factor SYF2 (PRP19 complex protein 31) (Synthetic lethal with CDC40 protein 2)
Gene: SYF2

Interactor 2: CLF1 (Q12309)
Pre-mRNA-splicing factor CLF1 (Crooked neck-like factor 1) (PRP19-associated complex protein 77) (Synthetic lethal with CDC40 protein 3)
Gene: CLF1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.925

The method score is based on:

Property Details
Experiments 11102353, 11842115, 16554755, 12509417, 37968396
Identification Methods two hybrid, affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains HAT~SYF2
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0000974 - Prp19 complex
GO:0071004 - U2-type prespliceosome
GO:0071006 - U2-type catalytic step 1 spliceosome
GO:0071007 - U2-type catalytic step 2 spliceosome
and 1 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 215
Sc

1 687
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024