Interactor 1: SLH1 (P53327)
RQC trigger complex helicase SLH1 (EC 3.6.4.13) (Antiviral helicase SLH1) (SKI2-like helicase 1)
Gene: SLH1

Interactor 2: HEL2 (Q05580)
E3 ubiquitin-protein ligase HEL2 (EC 2.3.2.27) (Histone E3 ligase 2) (RING-type E3 ubiquitin transferase HEL2)
Gene: HEL2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 0.60 0.601

The method score is based on:

Property Details
Experiments 28223409, 28757607
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0022626 - cytosolic ribosome
GO:0072344 - rescue of stalled ribosome
GO:1990116 - ribosome-associated ubiquitin-dependent protein catabolic process
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 1967
Sc

1 639
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024