Interactor 1: PLK1 (P53350)
Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)
Gene: PLK1

Interactor 2: CDC20 (Q12834)
Cell division cycle protein 20 homolog (p55CDC)
Gene: CDC20

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 0.60 0.694

The method score is based on:

Property Details
Experiments 23160376, 23643811, 26912231, 25659891
Identification Methods affinity chromatography technology, enzymatic study
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000776 - kinetochore
GO:0000922 - spindle pole
GO:0005654 - nucleoplasm
GO:0005813 - centrosome
GO:0005819 - spindle
and 6 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 603
Hs

1 499
+ Hs
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+ Dm
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+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024