Interactor 1: PLK1 (P53350)
Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)
Gene: PLK1
Interactor 2: TP53B (Q12888)
TP53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1)
Gene: TP53BP1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.89 | 0.60 | 0.732 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25607646, 20126263, 25659891, 26291670, 32707033 |
| Identification Methods | affinity chromatography technology, enzymatic study, pull down, protein kinase assay, anti bait coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, phosphorylation reaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000776 - kinetochore GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:2000042 - negative regulation of double-strand break repair via homologous recombination |
| Homologous interactions | 6 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
