HitPredict

Interactor 1: THO2 (P53552)
THO complex subunit 2 (Low dye-binding protein 5) (THO complex subunit RLR1) (Zinc-regulated gene 13 protein)
Gene: THO2

Interactor 2: YRA1 (Q12159)
RNA annealing protein YRA1
Gene: YRA1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.691

Property	Details
Experiments	11979277, 16554755, 17922018, 37399331
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000346 - transcription export complex GO:0003729 - mRNA binding GO:0005634 - nucleus GO:0006283 - transcription-coupled nucleotide-excision repair GO:0006368 - transcription elongation by RNA polymerase II and 1 others more... GO:0006406 - mRNA export from nucleus
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1597 Sc			1 226
+	Sc
		376876 THO2_YEAST (1-1597): 0: 1553: 100.00		PABP_YEAST (58-163): 4.29e-13: 69.8: 18.69
+	Hs
		1201103 THOC2_HUMAN (32-1589): 0: 1376: 16.89		THOC4_HUMAN (1-225): 3.86e-44: 150: 21.65
+	Hs
		92363 THOC2_HUMAN (32-1589): 0: 1376: 16.89		E9PB61_HUMAN (1-225): 1.5e-43: 148: 21.65
+	Hs
		1246365 THOC2_HUMAN (32-1589): 0: 1376: 16.89		PDIP3_HUMAN (33-195): 3.43e-28: 111: 18.68
+	Hs
		1132706 ZC3HD_HUMAN (1174-1597): 6.38e-13: 76.5: 10.38		THOC4_HUMAN (1-225): 3.86e-44: 150: 21.65
+	Hs
		1154073 NIPBL_HUMAN (1161-1585): 6.35e-17: 89.6: 8.48		PDIP3_HUMAN (33-195): 3.43e-28: 111: 18.68