HitPredict

Interactor 1: PGTB2 (P53611)
Geranylgeranyl transferase type-2 subunit beta (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit beta) (GGTase-II-beta) (Rab geranyl-geranyltransferase subunit beta) (Rab GG transferase beta) (Rab GGTase beta) (Rab geranylgeranyltransferase subunit beta) (Type II protein geranyl-geranyltransferase subunit beta)
Gene: RABGGTB

Interactor 2: RB40B (Q12829)
Ras-related protein Rab-40B (SOCS box-containing protein RAR) (Protein Rar)
Gene: RAB40B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 331 Hs			1 278
+	Hs
		863124 PGTB2_HUMAN (1-331): 0: 523: 100.00		RB40C_HUMAN (1-278): 8.54e-95: 282: 78.29
+	Dm
		185518 Q9XZ68_DROME (22-330): 3.01e-156: 442: 64.42		O18332_DROME (4-197): 5.86e-88: 262: 36.59
+	Dm
		185723 Q9XZ68_DROME (22-330): 3.01e-156: 442: 64.42		O18335_DROME (4-225): 1.88e-85: 256: 29.15
+	Hs
		863088 PGTB2_HUMAN (1-331): 0: 523: 100.00		RAB8A_HUMAN (9-172): 1.01e-46: 157: 47.27
+	Sc
		350843 PGTB2_YEAST (17-327): 2.34e-146: 417: 51.89		YPT1_YEAST (7-194): 1.04e-85: 256: 37.04
+	Hs
		863080 PGTB1_HUMAN (18-323): 1.81e-117: 345: 28.99		RAB2B_HUMAN (10-230): 1.09e-84: 254: 27.03