HitPredict

Interactor 1: COPB (P53618)
Coatomer subunit beta (Beta-coat protein) (Beta-COP)
Gene: COPB1

Interactor 2: SCYL1 (Q96KG9)
N-terminal kinase-like protein (Coated vesicle-associated kinase of 90 kDa) (SCY1-like protein 1) (Telomerase regulation-associated protein) (Telomerase transcriptional element-interacting factor) (Teratoma-associated tyrosine kinase)
Gene: SCYL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.619

Property	Details
Experiments	30631079, 35271311
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005793 - endoplasmic reticulum-Golgi intermediate compartment GO:0005794 - Golgi apparatus GO:0005829 - cytosol GO:0016020 - membrane GO:0030126 - COPI vesicle coat
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 953 Hs			1 808
+	Hs
		863266 COPB_HUMAN (1-953): 0: 1109: 100.00		PACE1_HUMAN (9-436): 4.41e-112: 360: 27.31
+	Sc
		784367 COPB_YEAST (2-952): 0: 894: 42.32		CEX1_YEAST (4-723): 3.05e-108: 350: 19.43
+	Rn
		923854 AP2B1_RAT (19-529): 1.43e-140: 444: 15.41		SCYL1_RAT (1-808): 0: 582: 90.25
+	Hs
		925914 AP2B1_HUMAN (19-529): 1.43e-140: 444: 15.41		SCYL2_HUMAN (13-805): 2.81e-121: 389: 16.91