Interactor 1: SPC1 (P46965)
Signal peptidase complex subunit 1 (Microsomal signal peptidase subunit 1)
Gene: SPC1
Interactor 2: SPC2 (Q04969)
Signal peptidase complex subunit 2 (Microsomal signal peptidase subunit 2)
Gene: SPC2
Species: Saccharomyces cerevisiae S288C
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.79 | 0.90 | 0.846 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16554755, 18467557, 37968396, 9148931 |
| Identification Methods | affinity chromatography technology, protein complementation assay, dihydrofolate reductase reconstruction, anti bait coimmunoprecipitation, tandem affinity purification |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | SPC12~SPC25 |
| Common GO terms | GO:0005783 - endoplasmic reticulum GO:0005787 - signal peptidase complex GO:0005789 - endoplasmic reticulum membrane GO:0006465 - signal peptide processing GO:0045047 - protein targeting to ER |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
