HitPredict

Interactor 1: COPA (P53622)
Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (Retrieval from endoplasmic reticulum protein 1) (Secretory protein 22) (Suppressor of osmo-sensitivity 1)
Gene: COP1

Interactor 2: ERV41 (Q04651)
ER-derived vesicles protein ERV41
Gene: ERV41

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	16429126, 37968396, 35904239
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006890 - retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1201 Sc			1 352
+	Hs
		863524 COPA_HUMAN (3-1199): 0: 1078: 42.67		ERGI2_HUMAN (1-320): 2.32e-109: 325: 27.96
+	Sc
		763781 COPA_YEAST (1-1201): 0: 1053: 100.00		ERV46_YEAST (2-335): 2.8e-109: 326: 18.78
+	Hs
		863510 COPA_HUMAN (3-1199): 0: 1078: 42.67		ERGI1_HUMAN (5-327): 1.18e-89: 272: 17.72
+	Hs
		725514 COPB2_HUMAN (1-909): 0: 562: 20.65		ERGI1_HUMAN (5-327): 1.18e-89: 272: 17.72
+	Sc
		784427 COPB2_YEAST (131-923): 2.71e-52: 201: 9.21		ERV41_YEAST (1-352): 1.51e-143: 411: 100.00
+	Sc
		763771 COPB2_YEAST (131-923): 2.71e-52: 201: 9.21		ERV46_YEAST (2-335): 2.8e-109: 326: 18.78
+	Hs
		903422 WDR5_HUMAN (408-680): 1.68e-50: 184: 8.50		ERGI1_HUMAN (5-327): 1.18e-89: 272: 17.72