Interactor 1: PAP2 (P53632)
Poly(A) RNA polymerase protein 2 (EC 2.7.7.19) (DNA polymerase kappa) (DNA polymerase sigma) (Topoisomerase 1-related protein TRF4)
Gene: PAP2

Interactor 2: AIR2 (Q12476)
Protein AIR2 (Arginine methyltransferase-interacting RING finger protein 2)
Gene: AIR2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.988

The method score is based on:

Property Details
Experiments 20696927, 20566885, 11805837, 24097436, 15935759, 15935758, 15828860, 16429126, 31768992, 32561742, 37968396, 22402490, 16554755, 19593367, 25066235, 21663793
Identification Methods pull down, x-ray crystallography, molecular sieving, ion exchange chromatography, anti tag coimmunoprecipitation, affinity chromatography technology, biochemical, tandem affinity purification, two hybrid
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PAP_assoc~zf-CCHC
Common GO terms GO:0000292 - RNA fragment catabolic process
GO:0005730 - nucleolus
GO:0006400 - tRNA modification
GO:0031499 - TRAMP complex
GO:0071031 - nuclear mRNA surveillance of mRNA 3'-end processing
and 5 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 584
Sc

1 344
+ Sc
+ Sc
+ Sc
+ Sp
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024