HitPredict

Interactor 1: LIMK1 (P53667)
LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)
Gene: LIMK1

Interactor 2: LIMK1 (P53667)
LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)
Gene: LIMK1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 1.00 0.812

The method score is based on:

Property Details
Experiments 8980133, 10559936
Identification Methods affinity chromatography technology, pull down, protein kinase assay
Interaction Type physical association, direct interaction, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains LIM~LIM, PDZ~PDZ, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr
Common GO terms GO:0001673 - male germ cell nucleus
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 23 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 647
Hs

1 647
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Last updated: 15 Jul 2024