HitPredict

Interactor 1: LIMK1 (P53667)
LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)
Gene: LIMK1

Interactor 2: LIMK2 (P53671)
LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1)
Gene: LIMK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.853

The method score is based on:

Property Details
Experiments 9089416, 8980133, 33961781
Identification Methods enzymatic study, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains LIM~LIM, PDZ~PDZ, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006468 - protein phosphorylation
and 3 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 647
Hs

1 638
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+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024