HitPredict

Interactor 1: LIMK1 (P53667)
LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)
Gene: LIMK1

Interactor 2: H90B4 (Q58FF6)
Putative heat shock protein HSP 90-beta 4
Gene: HSP90AB4P

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 647 Hs			1 505
+	Hs
		438022 LIMK1_HUMAN (1-647): 0: 622: 100.00		HS90B_HUMAN (1-504): 0: 671: 69.93
+	Hs
		431683 LIMK1_HUMAN (1-647): 0: 622: 100.00		HS90A_HUMAN (1-504): 0: 655: 62.96
+	Hs
		438023 LIMK2_HUMAN (18-640): 9.61e-175: 513: 52.80		HS90B_HUMAN (1-504): 0: 671: 69.93
+	Hs
		431684 LIMK2_HUMAN (18-640): 9.61e-175: 513: 52.80		HS90A_HUMAN (1-504): 0: 655: 62.96
+	Hs
		863830 LIMK2_HUMAN (18-640): 9.61e-175: 513: 52.80		H90B4_HUMAN (1-505): 0: 644: 100.00
+	Hs
		438029 EPHA4_HUMAN (6-641): 8.54e-143: 442: 17.90		HS90B_HUMAN (1-504): 0: 671: 69.93
+	Hs
		538167 LIMK2_HUMAN (18-640): 9.61e-175: 513: 52.80		ENPL_HUMAN (1-504): 0: 597: 35.70
+	Hs
		431562 EPHA3_HUMAN (7-642): 8.94e-145: 447: 17.27		HS90A_HUMAN (1-504): 0: 655: 62.96
+	Hs
		438028 EPHB1_HUMAN (14-630): 2.75e-137: 427: 18.20		HS90B_HUMAN (1-504): 0: 671: 69.93
+	Hs
		431692 EPHA4_HUMAN (6-641): 8.54e-143: 442: 17.90		HS90A_HUMAN (1-504): 0: 655: 62.96
+	Hs
		431691 EPHB1_HUMAN (14-630): 2.75e-137: 427: 18.20		HS90A_HUMAN (1-504): 0: 655: 62.96
+	Hs
		437918 EPHA2_HUMAN (14-644): 4.34e-131: 411: 17.93		HS90B_HUMAN (1-504): 0: 671: 69.93
+	Hs
		437860 BRAF_HUMAN (83-645): 2.36e-128: 398: 21.29		HS90B_HUMAN (1-504): 0: 671: 69.93
+	Hs
		431561 EPHA2_HUMAN (14-644): 4.34e-131: 411: 17.93		HS90A_HUMAN (1-504): 0: 655: 62.96
+	Hs
		431496 BRAF_HUMAN (83-645): 2.36e-128: 398: 21.29		HS90A_HUMAN (1-504): 0: 655: 62.96
+	Mm
		432406 BRAF_MOUSE (83-645): 5.66e-127: 394: 20.42		HS90A_MOUSE (1-504): 0: 652: 61.81
+	Hs
		538082 BRAF_HUMAN (83-645): 2.36e-128: 398: 21.29		ENPL_HUMAN (1-504): 0: 597: 35.70
+	Mm
		435915 BRAF_MOUSE (83-645): 5.66e-127: 394: 20.42		ENPL_MOUSE (1-504): 0: 600: 35.70
+	Gg
		435893 BRAF_CHICK (83-645): 1.53e-126: 393: 21.49		ENPL_CHICK (1-504): 0: 581: 35.88
+	Hs
		542890 BRAF_HUMAN (83-645): 2.36e-128: 398: 21.29		H90B3_HUMAN (1-504): 3.09e-143: 426: 58.87