HitPredict

Interactor 1: LIMK2 (P53671)
LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1)
Gene: LIMK2

Interactor 2: HS904 (Q58FG1)
Putative heat shock protein HSP 90-alpha A4 (Heat shock 90 kDa protein 1 alpha-like 2) (Heat shock protein 90-alpha D) (Heat shock protein 90Ad)
Gene: HSP90AA4P

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	32707033
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 638 Hs			1 418
+	Hs
		431684 LIMK2_HUMAN (1-638): 0: 577: 100.00		HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41
+	Hs
		438023 LIMK2_HUMAN (1-638): 0: 577: 100.00		HS90B_HUMAN (96-256): 4.57e-41: 156: 51.85
+	Hs
		538167 LIMK2_HUMAN (1-638): 0: 577: 100.00		ENPL_HUMAN (96-407): 1.36e-36: 144: 26.90
+	Hs
		863830 LIMK2_HUMAN (1-638): 0: 577: 100.00		H90B4_HUMAN (112-275): 1.78e-26: 112: 42.42
+	Hs
		431683 LIMK1_HUMAN (6-638): 1.03e-170: 503: 52.73		HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41
+	Hs
		438022 LIMK1_HUMAN (6-638): 1.03e-170: 503: 52.73		HS90B_HUMAN (96-256): 4.57e-41: 156: 51.85
+	Hs
		431691 EPHB1_HUMAN (7-632): 4.77e-154: 471: 17.54		HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41
+	Hs
		431562 EPHA3_HUMAN (7-629): 2.44e-151: 463: 18.27		HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41
+	Hs
		431692 EPHA4_HUMAN (7-631): 3.48e-149: 458: 18.13		HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41
+	Hs
		438028 EPHB1_HUMAN (7-632): 4.77e-154: 471: 17.54		HS90B_HUMAN (96-256): 4.57e-41: 156: 51.85
+	Hs
		863776 LIMK1_HUMAN (6-638): 1.03e-170: 503: 52.73		H90B4_HUMAN (112-275): 1.78e-26: 112: 42.42
+	Hs
		438029 EPHA4_HUMAN (7-631): 3.48e-149: 458: 18.13		HS90B_HUMAN (96-256): 4.57e-41: 156: 51.85
+	Hs
		431561 EPHA2_HUMAN (9-636): 4.26e-137: 426: 18.52		HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41
+	Hs
		431531 EPHA1_HUMAN (5-636): 6.05e-133: 416: 19.06		HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41
+	Hs
		437918 EPHA2_HUMAN (9-636): 4.26e-137: 426: 18.52		HS90B_HUMAN (96-256): 4.57e-41: 156: 51.85
+	Hs
		437892 EPHA1_HUMAN (5-636): 6.05e-133: 416: 19.06		HS90B_HUMAN (96-256): 4.57e-41: 156: 51.85
+	Hs
		538261 EPHAA_HUMAN (10-632): 5.95e-118: 377: 17.71		ENPL_HUMAN (96-407): 1.36e-36: 144: 26.90
+	Hs
		431880 TESK1_HUMAN (313-637): 6.25e-96: 309: 40.85		HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41
+	Hs
		438195 TESK1_HUMAN (313-637): 6.25e-96: 309: 40.85		HS90B_HUMAN (96-256): 4.57e-41: 156: 51.85
+	Hs
		432182 TESK2_HUMAN (335-610): 2.37e-60: 213: 40.86		HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41