HitPredict

Interactor 1: AP2S1 (P53680)
AP-2 complex subunit sigma (Adaptor protein complex AP-2 subunit sigma) (Adaptor-related protein complex 2 subunit sigma) (Clathrin assembly protein 2 sigma small chain) (Clathrin coat assembly protein AP17) (Clathrin coat-associated protein AP17) (HA2 17 kDa subunit) (Plasma membrane adaptor AP-2 17 kDa protein) (Sigma2-adaptin)
Gene: AP2S1

Interactor 2: BCAR1 (P56945)
Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (Cas scaffolding protein family member 1) (p130cas)
Gene: BCAR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28007913
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 142 Hs			1 870
+	Hs
		882466 AP3S1_HUMAN (1-142): 5.3e-51: 162: 40.54		BCAR1_HUMAN (1-870): 2.49e-107: 352: 100.00
+	Dm
		248311 O62530_DROME (1-138): 2.63e-42: 146: 16.67		Q9VLS7_DROME (65-706): 2.75e-10: 66.5: 9.08
+	Hs
		203244 AP2M1_HUMAN (1-138): 1.82e-41: 144: 15.22		SYNJ1_HUMAN (281-696): 4.9e-10: 65.7: 13.47