HitPredict

Interactor 1: AP2S1 (P53680)
AP-2 complex subunit sigma (Adaptor protein complex AP-2 subunit sigma) (Adaptor-related protein complex 2 subunit sigma) (Clathrin assembly protein 2 sigma small chain) (Clathrin coat assembly protein AP17) (Clathrin coat-associated protein AP17) (HA2 17 kDa subunit) (Plasma membrane adaptor AP-2 17 kDa protein) (Sigma2-adaptin)
Gene: AP2S1

Interactor 2: RBP1 (Q15311)
RalA-binding protein 1 (RalBP1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase) (EC 7.6.2.2, EC 7.6.2.3) (Ral-interacting protein 1)
Gene: RALBP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	28514442, 33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 142 Hs			1 655
+	Hs
		1071170 AP1M2_HUMAN (2-142): 3.16e-44: 151: 19.44		RBP1_HUMAN (1-655): 1.95e-168: 498: 100.00
+	Hs
		1071139 AP2M1_HUMAN (1-138): 1.82e-41: 144: 15.22		RBP1_HUMAN (1-655): 1.95e-168: 498: 100.00
+	Dm
		1363603 Q9VDC3_DROME (1-142): 1.92e-46: 149: 95.78		RLIP_DROME (27-595): 3.66e-82: 273: 28.73
+	Dm
		248305 O62530_DROME (1-138): 2.63e-42: 146: 16.67		RLIP_DROME (27-595): 3.66e-82: 273: 28.73
+	Hs
		506640 AP2M1_HUMAN (1-138): 1.82e-41: 144: 15.22		BCR_HUMAN (165-355): 8.32e-57: 210: 30.93
+	Hs
		902365 COPZ1_HUMAN (2-138): 3.65e-44: 144: 22.30		RGAP1_HUMAN (183-350): 2.03e-13: 75.5: 31.07