HitPredict

Interactor 1: AP2S1 (P53680)
AP-2 complex subunit sigma (Adaptor protein complex AP-2 subunit sigma) (Adaptor-related protein complex 2 subunit sigma) (Clathrin assembly protein 2 sigma small chain) (Clathrin coat assembly protein AP17) (Clathrin coat-associated protein AP17) (HA2 17 kDa subunit) (Plasma membrane adaptor AP-2 17 kDa protein) (Sigma2-adaptin)
Gene: AP2S1

Interactor 2: RUN3A (Q59EK9)
RUN domain-containing protein 3A (Rap2-interacting protein 8) (RPIP-8)
Gene: RUNDC3A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 142 Hs			1 446
+	Hs
		1123885 AP1M1_HUMAN (2-137): 4.68e-44: 150: 14.71		RUN3A_HUMAN (1-446): 4.01e-169: 484: 100.00
+	Hs
		1123878 AP2M1_HUMAN (1-138): 1.82e-41: 144: 15.22		RUN3A_HUMAN (1-446): 4.01e-169: 484: 100.00
+	Hs
		1267481 AP3S1_HUMAN (1-142): 5.3e-51: 162: 40.54		RUFY1_HUMAN (17-401): 9.69e-84: 273: 18.75
+	Hs
		1302803 AP1M2_HUMAN (2-142): 3.16e-44: 151: 19.44		RUFY1_HUMAN (17-401): 9.69e-84: 273: 18.75
+	Hs
		1302752 AP1M1_HUMAN (2-137): 4.68e-44: 150: 14.71		RUFY1_HUMAN (17-401): 9.69e-84: 273: 18.75
+	Hs
		1256639 AP2M1_HUMAN (1-138): 1.82e-41: 144: 15.22		SNX29_HUMAN (19-410): 5.69e-47: 174: 15.86