HitPredict

Interactor 1: AP2S1 (P53680)
AP-2 complex subunit sigma (Adaptor protein complex AP-2 subunit sigma) (Adaptor-related protein complex 2 subunit sigma) (Clathrin assembly protein 2 sigma small chain) (Clathrin coat assembly protein AP17) (Clathrin coat-associated protein AP17) (HA2 17 kDa subunit) (Plasma membrane adaptor AP-2 17 kDa protein) (Sigma2-adaptin)
Gene: AP2S1

Interactor 2: ARFG1 (Q8N6T3)
ADP-ribosylation factor GTPase-activating protein 1 (ARF GAP 1) (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase-activating protein)
Gene: ARFGAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016192 - vesicle-mediated transport GO:0030100 - regulation of endocytosis
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 142 Hs			1 406
+	Hs
		1236356 AP2M1_HUMAN (1-138): 1.82e-41: 144: 15.22		ARFG1_HUMAN (1-406): 1.23e-119: 355: 100.00
+	Rn
		950918 AP2M1_RAT (1-138): 1.82e-41: 144: 15.22		ARFG1_RAT (1-406): 5.99e-112: 335: 82.93
+	Zm
		42706 B4FTQ9_MAIZE (2-140): 3.12e-43: 141: 41.73		A0A1D6P636_MAIZE (2-347): 1.12e-58: 199: 21.27