HitPredict

Interactor 1: NOG2 (P53742)
Nucleolar GTP-binding protein 2
Gene: NOG2

Interactor 2: NOG1 (Q02892)
Nucleolar GTP-binding protein 1
Gene: NOG1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.754

Property	Details
Experiments	12808088, 11707418, 16429126, 29294095, 23874617, 16554755, 27251291, 27390266, 33037216, 37968396, 24240281
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005730 - nucleolus GO:0030687 - preribosome, large subunit precursor
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 486 Sc			1 647
+	Hs
		1045686 NOG2_HUMAN (4-472): 6.46e-161: 475: 52.87		GTPB4_HUMAN (2-647): 0: 653: 46.06
+	Dm
		1177943 Q7JXU4_DROME (11-482): 1.59e-152: 451: 48.33		NOG1_DROME (3-647): 0: 577: 47.13
+	Sc
		859624 LSG1_YEAST (97-484): 1.98e-100: 316: 21.09		NOG1_YEAST (1-647): 0: 628: 100.00
+	Sc
		766687 NUG1_YEAST (91-483): 1.8e-90: 287: 24.71		NOG1_YEAST (1-647): 0: 628: 100.00
+	Dm
		1229281 GNL3_DROME (89-475): 6.14e-97: 305: 27.49		NOG1_DROME (3-647): 0: 577: 47.13
+	Hs
		1045737 NOG2_HUMAN (4-472): 6.46e-161: 475: 52.87		DRG1_HUMAN (98-494): 3.82e-81: 262: 14.22
+	Hs
		1314114 GNL3_HUMAN (84-482): 2.27e-106: 329: 27.57		DRG1_HUMAN (98-494): 3.82e-81: 262: 14.22
+	Hs
		1327329 LSG1_HUMAN (45-290): 7.08e-50: 182: 18.73		DRG1_HUMAN (98-494): 3.82e-81: 262: 14.22
+	Hs
		59634 MTG1_HUMAN (201-467): 5.75e-67: 220: 23.31		GTPBA_HUMAN (167-362): 5.62e-42: 158: 18.83
+	Ec
		633785 MNME_ECOLI (107-405): 2.12e-48: 174: 15.79		MNME_ECOLI (138-333): 2.14e-15: 81: 25.00