HitPredict

Interactor 1: ESF2 (P53743)
Pre-rRNA-processing protein ESF2 (18S rRNA factor 2)
Gene: ESF2

Interactor 2: HAS1 (Q03532)
ATP-dependent RNA helicase HAS1 (EC 3.6.4.13) (Helicase associated with SET1 protein 1)
Gene: HAS1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.637

Property	Details
Experiments	15964808, 29054886
Identification Methods	affinity chromatography technology, two hybrid, two hybrid array, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005730 - nucleolus GO:0030490 - maturation of SSU-rRNA GO:0032040 - small-subunit processome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 316 Sc			1 505
+	Sc
		593674 ESF2_YEAST (1-316): 4.63e-116: 339: 100.00		DBP4_YEAST (3-501): 9.9e-165: 486: 37.70
+	Hs
		1245892 ABT1_HUMAN (69-316): 1e-102: 303: 24.02		DDX55_HUMAN (43-486): 6.51e-172: 499: 37.45
+	Hs
		1027944 ABT1_HUMAN (69-316): 1e-102: 303: 24.02		DDX10_HUMAN (5-505): 1.4e-148: 448: 37.87
+	Hs
		1333562 ABT1_HUMAN (69-316): 1e-102: 303: 24.02		DDX31_HUMAN (9-505): 3.72e-82: 274: 32.37
+	Sc
		753040 ESF2_YEAST (1-316): 4.63e-116: 339: 100.00		RRP3_YEAST (24-392): 1.96e-69: 232: 38.11
+	Hs
		1292683 ABT1_HUMAN (69-316): 1e-102: 303: 24.02		DDX27_HUMAN (44-441): 4.37e-71: 243: 37.04
+	Hs
		1328103 ABT1_HUMAN (69-316): 1e-102: 303: 24.02		DDX47_HUMAN (1-411): 5.57e-74: 242: 36.96
+	Hs
		1357106 ABT1_HUMAN (69-316): 1e-102: 303: 24.02		DDX49_HUMAN (44-429): 8.79e-60: 206: 34.52