HitPredict

Interactor 1: MLP1 (P53777)
Muscle LIM protein 1
Gene: Mlp60A

Interactor 2: LIMK1 (Q8IR79)
LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1) (dLIMK)
Gene: LIMK1

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	37061542
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	LIM~LIM
Common GO terms	GO:0005634 - nucleus GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 92 Dm			1 1257
+	Dm
		81122 B7YZP9_DROME (4-84): 1.7e-14: 68.8: 35.37		LIMK1_DROME (1-1257): 0: 920: 100.00
+	Mm
		222366 PAXI_MOUSE (3-67): 8.04e-16: 72.5: 23.08		LIMK2_MOUSE (22-723): 2.6e-154: 479: 36.36
+	Mm
		863810 PAXI_MOUSE (3-67): 8.04e-16: 72.5: 23.08		LIMK1_MOUSE (16-726): 4.91e-149: 466: 40.34
+	Hs
		337395 PAXI_HUMAN (3-67): 6.68e-16: 72.9: 24.62		ABL1_HUMAN (194-1236): 1.64e-131: 434: 15.37
+	Mm
		337635 PAXI_MOUSE (3-67): 8.04e-16: 72.5: 23.08		ABL1_MOUSE (194-1209): 1.83e-131: 433: 15.92
+	Mm
		1257660 PAXI_MOUSE (3-67): 8.04e-16: 72.5: 23.08		FAK2_MOUSE (297-808): 2.13e-114: 384: 19.86
+	Hs
		823394 PAXI_HUMAN (3-67): 6.68e-16: 72.9: 24.62		FAK2_HUMAN (297-808): 9.38e-107: 362: 19.00
+	Hs
		433500 LIMA1_HUMAN (2-77): 2.47e-25: 99.5: 28.95		YES_HUMAN (322-703): 1.02e-91: 308: 23.64
+	Hs
		412085 PAXI_HUMAN (3-67): 6.68e-16: 72.9: 24.62		FYN_HUMAN (322-703): 1.24e-95: 319: 25.20
+	Hs
		254384 LDB3_HUMAN (3-64): 5.23e-17: 76: 25.40		SRC_HUMAN (322-703): 6.62e-94: 313: 24.02
+	Hs
		522857 PAXI_HUMAN (3-67): 6.68e-16: 72.9: 24.62		SRC_HUMAN (322-703): 6.62e-94: 313: 24.02
+	Mm
		403454 PAXI_MOUSE (3-67): 8.04e-16: 72.5: 23.08		SRC_MOUSE (322-703): 1.21e-92: 310: 23.76
+	Hs
		433288 PAXI_HUMAN (3-67): 6.68e-16: 72.9: 24.62		YES_HUMAN (322-703): 1.02e-91: 308: 23.64
+	Hs
		111447 PDLI7_HUMAN (3-62): 3.8e-15: 70.6: 24.59		J3QRU1_HUMAN (322-703): 1.18e-91: 308: 23.64
+	Hs
		433484 PDLI7_HUMAN (3-62): 3.8e-15: 70.6: 24.59		YES_HUMAN (322-703): 1.02e-91: 308: 23.64
+	Hs
		412099 LIMK1_HUMAN (3-65): 4.7e-11: 59: 24.62		FYN_HUMAN (322-703): 1.24e-95: 319: 25.20
+	Hs
		433354 LASP1_HUMAN (8-63): 2.81e-13: 64.6: 33.93		YES_HUMAN (322-703): 1.02e-91: 308: 23.64
+	Hs
		1301720 LIMA1_HUMAN (2-77): 2.47e-25: 99.5: 28.95		TESK2_HUMAN (394-692): 3.17e-59: 216: 40.52
+	Hs
		561402 LIMA1_HUMAN (2-77): 2.47e-25: 99.5: 28.95		FER_HUMAN (395-683): 6.17e-29: 127: 29.07
+	Hs
		150581 ABLM1_HUMAN (1-78): 2.38e-11: 59.8: 18.39		NTRK2_HUMAN (374-690): 1.21e-24: 113: 28.53