HitPredict

Interactor 1: MK12 (P53778)
Mitogen-activated protein kinase 12 (MAP kinase 12) (MAPK 12) (EC 2.7.11.24) (Extracellular signal-regulated kinase 6) (ERK-6) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) (Stress-activated protein kinase 3)
Gene: MAPK12

Interactor 2: DLG1 (Q12959)
Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg)
Gene: DLG1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	27416801, 30126976
Identification Methods	affinity chromatography technology, p8 filamentous phage display
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 367 Hs			1 904
+	Mm
		140069 MK12_MOUSE (1-367): 1.68e-156: 445: 92.64		DLG1_MOUSE (1-904): 0: 720: 95.47
+	Rn
		1144013 MK12_RAT (1-367): 3.98e-157: 447: 93.73		DLG1_RAT (1-904): 0: 701: 92.54
+	Mm
		814054 MK14_MOUSE (5-363): 2.06e-145: 417: 61.56		DLG1_MOUSE (1-904): 0: 720: 95.47
+	Rn
		926488 MK01_RAT (13-357): 1.6e-141: 407: 40.63		DLG3_RAT (99-904): 0: 590: 64.57
+	Hs
		864827 MK12_HUMAN (1-367): 2.48e-155: 443: 100.00		SCRIB_HUMAN (217-396): 1.59e-23: 109: 41.49
+	Rn
		677771 MK01_RAT (13-357): 1.6e-141: 407: 40.63		DLG4_RAT (86-493): 2.93e-24: 111: 15.40
+	Mm
		926414 MK01_MOUSE (13-357): 1.6e-141: 407: 40.63		DLG4_MOUSE (86-477): 2.03e-24: 111: 16.07
+	Hs
		658937 MK01_HUMAN (13-357): 2.07e-141: 407: 40.63		SCRIB_HUMAN (217-396): 1.59e-23: 109: 41.49
+	Hs
		647575 MK03_HUMAN (14-353): 2.84e-136: 394: 42.08		SCRIB_HUMAN (217-396): 1.59e-23: 109: 41.49
+	Hs
		658938 MK01_HUMAN (13-357): 2.07e-141: 407: 40.63		MPP2_HUMAN (134-320): 5.48e-13: 74.9: 16.84
+	Hs
		800840 MK08_HUMAN (9-367): 3.51e-105: 317: 44.00		ZO2_HUMAN (435-711): 1.38e-13: 77.2: 17.13