HitPredict

Interactor 1: RPAB4 (P53803)
DNA-directed RNA polymerases I, II, and III subunit RPABC4 (RNA polymerases I, II, and III subunit ABC4) (ABC10-alpha) (DNA-directed RNA polymerase II subunit K) (RNA polymerase II 7.0 kDa subunit) (RPB7.0) (RPB10alpha)
Gene: POLR2K

Interactor 2: RPB7 (P62487)
DNA-directed RNA polymerase II subunit RPB7 (RNA polymerase II subunit B7) (DNA-directed RNA polymerase II subunit G) (RNA polymerase II 19 kDa subunit) (RPB19)
Gene: POLR2G

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.660

Property	Details
Experiments	24981860, 9201987, 35271311
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005665 - RNA polymerase II, core complex GO:0006366 - transcription by RNA polymerase II
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 58 Hs			1 172
+	Sp
		145814 RPAB4_SCHPO (8-58): 1.03e-22: 82.8: 54.90		RPB7_SCHPO (2-171): 1.24e-67: 205: 49.42
+	Hs
		865021 RPAB4_HUMAN (1-58): 1.96e-26: 92.1: 100.00		RPC8_HUMAN (1-172): 5.28e-54: 171: 18.72
+	Sc
		710017 RPAB4_YEAST (11-58): 2.14e-17: 69.7: 45.83		RPB7_YEAST (1-171): 4.45e-63: 193: 42.78
+	Sc
		727974 RPAB4_YEAST (11-58): 2.14e-17: 69.7: 45.83		RPC8_YEAST (1-158): 1.07e-49: 160: 19.39