HitPredict

Interactor 1: TTC3 (P53804)
E3 ubiquitin-protein ligase TTC3 (EC 2.3.2.27) (Protein DCRR1) (RING finger protein 105) (RING-type E3 ubiquitin transferase TTC3) (TPR repeat protein D) (Tetratricopeptide repeat protein 3) (TPR repeat protein 3)
Gene: TTC3

Interactor 2: Z3H7A (Q8IWR0)
Zinc finger CCCH domain-containing protein 7A
Gene: ZC3H7A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2025 Hs			1 971
+	Hs
		865078 TTC3_HUMAN (1-2025): 0: 1957: 100.00		DNJC7_HUMAN (15-196): 1.49e-15: 82.6: 23.91
+	Hs
		1219195 RN214_HUMAN (1461-1998): 7.04e-101: 343: 20.90		Z3H7A_HUMAN (1-971): 0: 1124: 100.00
+	Hs
		1242058 RN214_HUMAN (1461-1998): 7.04e-101: 343: 20.90		Z3H7B_HUMAN (7-969): 0: 1074: 44.56
+	Hs
		1051353 DCTN1_HUMAN (1227-1708): 2.17e-62: 237: 13.50		Z3H7A_HUMAN (1-971): 0: 1124: 100.00
+	Hs
		1205098 DZIP3_HUMAN (522-739): 1.71e-38: 160: 27.03		Z3H7A_HUMAN (1-971): 0: 1124: 100.00
+	Hs
		1332490 RPAP3_HUMAN (167-474): 7.92e-34: 142: 19.62		RPAP3_HUMAN (14-490): 2.16e-69: 246: 13.33
+	Hs
		297056 TOM70_HUMAN (224-631): 8.39e-55: 205: 13.83		FKBP5_HUMAN (3-225): 1.9e-42: 163: 13.54
+	Hs
		684714 DCTN1_HUMAN (1227-1708): 2.17e-62: 237: 13.50		STIP1_HUMAN (40-400): 6.8e-30: 127: 10.41
+	Mm
		1141207 PPP5_MOUSE (220-360): 1.31e-43: 169: 30.50		PPP5_MOUSE (23-214): 1.2e-43: 168: 19.39
+	Hs
		858598 PPP5_HUMAN (220-360): 6.34e-43: 167: 29.79		PPP5_HUMAN (23-214): 3.34e-44: 169: 19.90
+	Hs
		858619 PPP5_HUMAN (220-360): 6.34e-43: 167: 29.79		FKBP5_HUMAN (3-225): 1.9e-42: 163: 13.54
+	Hs
		1290144 SGTB_HUMAN (223-348): 1.29e-42: 160: 26.19		SGTB_HUMAN (3-276): 5.67e-46: 169: 15.16
+	Hs
		213621 SGTB_HUMAN (223-348): 1.29e-42: 160: 26.19		SGTA_HUMAN (6-277): 1.62e-45: 168: 15.07
+	Dm
		1368585 Q9VJD4_DROME (214-436): 1.24e-41: 158: 20.52		Q9VJD4_DROME (13-276): 1.4e-42: 160: 19.32
+	Ps
		1341481 TOC64_PEA (21-347): 4.32e-63: 229: 20.94		TOC64_PEA (23-170): 1.02e-16: 86.9: 24.32
+	Hs
		1034998 RPAP3_HUMAN (167-474): 7.92e-34: 142: 19.62		FKBP5_HUMAN (3-225): 1.9e-42: 163: 13.54
+	Hs
		684549 PPP5_HUMAN (220-360): 6.34e-43: 167: 29.79		STIP1_HUMAN (40-400): 6.8e-30: 127: 10.41
+	Dm
		1366835 Q9VH81_DROME (231-348): 2.45e-32: 136: 34.75		Q9VPN5_DROME (40-400): 1.07e-37: 150: 12.43
+	Hs
		213490 STIP1_HUMAN (74-510): 1.57e-24: 112: 13.23		SGTA_HUMAN (6-277): 1.62e-45: 168: 15.07
+	Hs
		685029 RPAP3_HUMAN (167-474): 7.92e-34: 142: 19.62		STIP1_HUMAN (40-400): 6.8e-30: 127: 10.41