HitPredict

Interactor 1: TTC3 (P53804)
E3 ubiquitin-protein ligase TTC3 (EC 2.3.2.27) (Protein DCRR1) (RING finger protein 105) (RING-type E3 ubiquitin transferase TTC3) (TPR repeat protein D) (Tetratricopeptide repeat protein 3) (TPR repeat protein 3)
Gene: TTC3

Interactor 2: DNJC7 (Q99615)
DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2)
Gene: DNAJC7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33957083
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 2025 Hs			1 494
+	Hs
		1028059 TGO1_HUMAN (1104-1863): 1.22e-83: 308: 14.29		DNJC3_HUMAN (14-289): 8.21e-26: 112: 17.83
+	Hs
		684975 STIP1_HUMAN (74-510): 1.57e-24: 112: 13.23		DNJC7_HUMAN (1-494): 2.58e-85: 273: 100.00
+	Hs
		684714 DCTN1_HUMAN (1227-1708): 2.17e-62: 237: 13.50		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Hs
		174501 TOM70_HUMAN (224-631): 8.39e-55: 205: 13.83		OGT1_HUMAN (3-401): 1.62e-31: 130: 13.59
+	Hs
		672831 DCTN1_HUMAN (1227-1708): 2.17e-62: 237: 13.50		CDC27_HUMAN (4-128): 1.63e-15: 81.6: 20.80
+	Hs
		297080 TOM70_HUMAN (224-631): 8.39e-55: 205: 13.83		TTC28_HUMAN (1-320): 1.04e-19: 95.1: 15.27
+	Hs
		174743 PPP5_HUMAN (220-360): 6.34e-43: 167: 29.79		OGT1_HUMAN (3-401): 1.62e-31: 130: 13.59
+	Hs
		684549 PPP5_HUMAN (220-360): 6.34e-43: 167: 29.79		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Mm
		1141207 PPP5_MOUSE (220-360): 1.31e-43: 169: 30.50		PPP5_MOUSE (139-260): 3.58e-16: 82.8: 13.93
+	Hs
		672793 PPP5_HUMAN (220-360): 6.34e-43: 167: 29.79		CDC27_HUMAN (4-128): 1.63e-15: 81.6: 20.80
+	Hs
		685029 RPAP3_HUMAN (167-474): 7.92e-34: 142: 19.62		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Hs
		174661 STIP1_HUMAN (74-510): 1.57e-24: 112: 13.23		OGT1_HUMAN (3-401): 1.62e-31: 130: 13.59
+	Dm
		1366835 Q9VH81_DROME (231-348): 2.45e-32: 136: 34.75		Q9VPN5_DROME (7-171): 3.79e-22: 101: 29.09
+	Hs
		858598 PPP5_HUMAN (220-360): 6.34e-43: 167: 29.79		PPP5_HUMAN (242-391): 7.28e-09: 60.1: 31.79
+	Hs
		684432 STIP1_HUMAN (74-510): 1.57e-24: 112: 13.23		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Hs
		1332490 RPAP3_HUMAN (167-474): 7.92e-34: 142: 19.62		RPAP3_HUMAN (2-223): 2.82e-09: 61.6: 11.92
+	Hs
		279279 STIP1_HUMAN (74-510): 1.57e-24: 112: 13.23		DNJB5_HUMAN (380-491): 5.82e-19: 90.1: 43.31
+	Hs
		684896 STIP1_HUMAN (74-510): 1.57e-24: 112: 13.23		DNJB8_HUMAN (381-482): 1.21e-15: 78.2: 44.35